E3ISPM45000KPA Microscopy Cameras/Microscope Cameras
Product Introduction
The E3ISPM series represents C-mount USB3.0 hardware ISP cameras featuring Sony Exmor/Exmor R/Exmor RS back-illuminated CMOS sensors, combining high sensitivity with low readout noise. The integrated 12-bit Ultra-Fine hardware ISP video stream engine completes demosaicing, auto exposure/gain, one-touch white balance, color/saturation/gamma/brightness/contrast processing and other real-time operations within the camera, significantly reducing host CPU utilization while improving transmission stability.
The cameras support real-time 8/12-bit switching and arbitrary ROI functionality, with resolution coverage from 1.5 MP to 45 MP. The USB3.0 high-speed link ensures smooth preview and acquisition performance. The housing features precision-machined zinc-aluminum alloy CNC construction for robust reliability and long-term stability. Bundled with ToupView/ToupLite software and cross-platform SDK support (Windows/Linux/macOS/Android) for seamless system integration and secondary development.
Typical applications include brightfield/darkfield/low-light and fluorescence microscopy, biomedical image analysis, semiconductor and materials inspection, industrial online inspection.
Key Features
- Back-illuminated CMOS sensors (Sony Exmor/Exmor R/Exmor RS, depending on model) with high sensitivity and low noise
- 12-bit Ultra-Fine hardware ISP: Demosaic, AE/AGC, AWB, one-touch white balance, color/saturation, gamma, brightness/contrast processing
- Parallel A/D architecture balancing low noise with low power consumption
- Bit depth and data: Real-time 8/12-bit switching with RAW/Bayer output support (depending on model)
- Resolution coverage from 1.5–45 MP (depending on model) meeting diverse requirements from educational to research/industrial scenarios
- Arbitrary ROI/windowing for flexible balance of resolution, frame rate and bandwidth
- USB3.0 (5 Gbit/s) high-speed transmission for stable preview and recording
- Zinc-aluminum alloy CNC housing with robust construction and excellent heat dissipation and shielding performance
- C-mount standard lens interface compatible with various microscopy and industrial optical systems
- Support for free-running, software/hardware trigger modes
- Bundled ToupView/ToupLite software with Windows/Linux/macOS/Android SDK, compatible with DirectShow/TWAIN
- Support for field firmware upgrades, compliant with CE/FCC/RoHS standards (depending on model)
Product Details
| Key Parameters | |
| Model | E3ISPM45000KPA |
| Sensor | IMX294 (C) |
| Effective Pixels / Resolution | 45M (8176×5616) |
| Frame Rate (Full Resolution) | 8.1 fps@8176×5616; 30.0 fps@4088×2808; 8.1 fps@7408×5556; 33.0 fps@4088×2808; 10.4 fps@8176×4320; 34.7 fps@4096×2160; 62.5 fps@2048×1080; 86.5 fps@1344×720 |
| Shutter Type | Rolling Shutter |
| Color Type | Color |
| Imaging Performance | |
| Pixel Size | 2.315 µm × 2.315 µm |
| Sensor Size | 18.93 mm × 13.00 mm |
| Diagonal | 1.4" |
| Dynamic Range | TBD |
| Bit Depth | 8/12-bit |
| Sensitivity | 108 mV with 1/30s; 0.03 mV with 1/30s |
| Interface & Mechanical | |
| Data Interface | USB3.0 |
| GPIO | TBD |
| Lens Mount | C-mount |
| Dimensions | TBD |
| Weight | TBD |
| Power Supply | USB3.0 interface power (compatible with USB2.0) |
| Environment & Certification | |
| Operating Temperature / Humidity | -10 °C ~ +50 °C / 30%~80%RH |
| Storage Temperature / Humidity | -20 °C ~ +60 °C / 10%~60%RH |
| Operating System | Windows/Linux/macOS/Android multi-platform SDK (native C/C++, C#/VB.NET, Python, Java, DirectShow, TWAIN, etc.) |
| Certification | CE, FCC |
Product Overview
E3ISPM45000KPA is a digital camera specifically designed for microscopic imaging applications, featuring a IMX294 (C) high-performance image sensor with the following characteristics:
- Exceptional Imaging Quality: 45M (8176×5616) resolution with 2.315 µm × 2.315 µm pixel size, sensor size of 18.93 mm × 13.00 mm , ensuring clear detail presentation
- Imaging Characteristics: Features Rolling Shutter design, supports color imaging, suitable for brightfield, darkfield, phase contrast, fluorescence and other microscopy observation methods
- High-Speed Data Transfer: Utilizes USB3.0 interface with maximum frame rate up to 8.1 fps@8176×5616; 30.0 fps@4088×2808; 8.1 fps@7408×5556; 33.0 fps@4088×2808; 10.4 fps@8176×4320; 34.7 fps@4096×2160; 62.5 fps@2048×1080; 86.5 fps@1344×720 , supporting real-time preview and rapid capture
- Color Reproduction: 8/12-bit color depth with dynamic range reaching TBD , accurately reproducing sample colors
- Sensitivity Performance: Excellent low-light performance with sensitivity of 108 mV with 1/30s; 0.03 mV with 1/30s , suitable for low-light sample observation
- Optical Compatibility: Standard C-mount interface, compatible with various microscope brands, optional 0.5×/0.63×/1× adapters available
- Compact Design: Overall dimensions of only TBD , weighing TBD , powered by USB3.0 interface power (compatible with USB2.0) , no additional power supply required
- Software Support: Includes professional microscopy imaging software ToupView, supports Windows/Linux/macOS/Android multi-platform SDK (native C/C++, C#/VB.NET, Python, Java, DirectShow, TWAIN, etc.) systems, provides measurement, annotation, stitching, focus stacking and other functions, supports C/C++, C#, Python, ImageJ, μManager development environments
Core Performance Indicators
Resolution
45M (8176×5616)
Frame Rate
Up to 8.1 fps@8176×5616; 30.0 fps@4088×2808; 8.1 fps@7408×5556; 33.0 fps@4088×2808; 10.4 fps@8176×4320; 34.7 fps@4096×2160; 62.5 fps@2048×1080; 86.5 fps@1344×720
Pixel Size
2.315 µm × 2.315 µm
Data Interface
USB3.0
Microscopic Imaging Features
Professional Microscopy Applications
Optimized for biomedical, materials science, and industrial inspection microscopy needs, supports brightfield, darkfield, phase contrast, fluorescence and other observation methods
Excellent Color Reproduction
Precise color reproduction algorithms and white balance control ensure accurate and true sample colors, meeting professional needs such as pathological diagnosis
Measurement and Analysis Functions
Bundled software provides measurement tools for length, area, angle, etc., supports annotation and statistical analysis, meeting quantitative analysis requirements
Image Processing Capabilities
Supports real-time image enhancement, focus stacking, image stitching and other advanced functions, improving observation effects and imaging quality
Why Choose This Camera
The E3ISPM45000KPA microscopy camera, with its excellent imaging quality, convenient operation experience, and professional software support, is an ideal choice for microscope digital upgrades. Whether for biomedical research, material analysis, or industrial inspection, it provides clear, accurate, and reliable microscopic image recording and analysis solutions.
E3ISPM45000KPA Product Manual
PDF format, includes detailed technical specifications and dimensional structure
SDK Development Kit
Supports Windows, Linux, macOS and other platforms
3D Model Files
STEP format, for mechanical design integration
Frequently Asked Questions
Learn more about the professional features of E3ISPM series microscopy imaging cameras
- Real-Time Processing: Ultra-Fine™ HISP VP completes demosaicing, auto exposure, white balance, and color correction inside the camera
- High-Quality Output: Direct output of 8/12-bit high-quality images without post-processing
- Low CPU Usage: Dramatically reduces computer CPU load, improving overall system efficiency
- Zero-Latency Imaging: Reduces backend processing delays for true "instant capture"
Hardware ISP Integration: Unique in its class for integrating 12-bit ISP within the camera body for more stable performance.
Research-Grade Image Quality: Maintains professional imaging quality while effectively controlling costs, outstanding cost-performance ratio.
Complete Ecosystem: Provides ToupView/ToupLite software and open-source SDK, reducing secondary development costs.
In-Depth Product Introduction
Ultra-Fine™ HISP VP Hardware ISP Engine
Features our proprietary 12-bit hardware image signal processor that performs real-time demosaicing, auto exposure control, auto white balance, and color correction inside the camera. Compared to software ISP, processing speed is improved by more than 10× with latency reduced to microsecond levels, achieving true "what you see is what you get" at the microscope.
Sony Exmor Back-Illuminated CMOS Technology
Features the latest Sony Exmor back-illuminated CMOS sensors with quantum efficiency >70% and dark current <0.1 e⁻/pix/s. The back-illuminated structure significantly improves photoelectric conversion efficiency, particularly suitable for low-light and fluorescence imaging applications, delivering clear images even under extremely low illumination conditions.
USB 3.0 High-Speed Data Transfer
Utilizes USB 3.0 SuperSpeed interface with bandwidth up to 5 Gbps, maintaining real-time preview at over 10 fps even for 45-megapixel models. No additional power supply required, plug-and-play compatibility with various microscope systems.
Flexible Imaging Modes
Supports arbitrary ROI area selection, 2×2/3×3/4×4 pixel binning, and 8-bit/12-bit data depth switching. Exposure time adjustable from 0.1 ms to 15 s, meeting comprehensive requirements from high-speed dynamic observation to long-term accumulative exposure.
Complete Hardware and Software Ecosystem
Provides multi-platform support for Windows/Linux/macOS, bundled with ToupView professional acquisition software and ToupLite lightweight tools. Open SDK interfaces including C/C++, C#/VB.NET, DirectShow, and Twain facilitate system integration and secondary development. All-metal CNC housing design with no fans or mechanical moving parts ensures long-term stable operation.
Key Application Areas
E3ISPM series applications across various microscopy imaging fields
E3ISPM Series Core Advantages
12-Bit Hardware ISP
Ultra-Fine™ HISP VP real-time processing engine
Sony Exmor CMOS
Back-illuminated sensors, quantum efficiency >70%
USB 3.0 High-Speed Transfer
45 MP maintains 10+ fps preview
Flexible Imaging Modes
Arbitrary ROI + multiple pixel binning
Cross-Platform SDK
Windows/Linux/macOS full coverage
Industrial-Grade Design
All-metal CNC housing, fanless silent
Ultra-Low Dark Current
<0.1 e⁻/pix/s, suitable for long exposure
High Cost-Performance
Research-grade image quality, controlled costs