E3ISPM Series
Product Introduction
                                    The E3ISPM series represents C-mount USB3.0 hardware ISP cameras featuring Sony Exmor/Exmor R/Exmor RS back-illuminated CMOS sensors, combining high sensitivity with low readout noise. The integrated 12-bit Ultra-Fine hardware ISP video stream engine completes demosaicing, auto exposure/gain, one-touch white balance, color/saturation/gamma/brightness/contrast processing and other real-time operations within the camera, significantly reducing host CPU utilization while improving transmission stability.
The cameras support real-time 8/12-bit switching and arbitrary ROI functionality, with resolution coverage from 1.5 MP to 45 MP. The USB3.0 high-speed link ensures smooth preview and acquisition performance. The housing features precision-machined zinc-aluminum alloy CNC construction for robust reliability and long-term stability. Bundled with ToupView/ToupLite software and cross-platform SDK support (Windows/Linux/macOS/Android) for seamless system integration and secondary development.
Typical applications include brightfield/darkfield/low-light and fluorescence microscopy, biomedical image analysis, semiconductor and materials inspection, industrial online inspection.                                
Product Features
- Back-illuminated CMOS sensors (Sony Exmor/Exmor R/Exmor RS, depending on model) with high sensitivity and low noise
 - 12-bit Ultra-Fine hardware ISP: Demosaic, AE/AGC, AWB, one-touch white balance, color/saturation, gamma, brightness/contrast processing
 - Parallel A/D architecture balancing low noise with low power consumption
 - Bit depth and data: Real-time 8/12-bit switching with RAW/Bayer output support (depending on model)
 - Resolution coverage from 1.5–45 MP (depending on model) meeting diverse requirements from educational to research/industrial scenarios
 - Arbitrary ROI/windowing for flexible balance of resolution, frame rate and bandwidth
 
- USB3.0 (5 Gbit/s) high-speed transmission for stable preview and recording
 - Zinc-aluminum alloy CNC housing with robust construction and excellent heat dissipation and shielding performance
 - C-mount standard lens interface compatible with various microscopy and industrial optical systems
 - Support for free-running, software/hardware trigger modes
 - Bundled ToupView/ToupLite software with Windows/Linux/macOS/Android SDK, compatible with DirectShow/TWAIN
 - Support for field firmware upgrades, compliant with CE/FCC/RoHS standards (depending on model)
 
Product Models
Select the E3ISPM Series that fits your application requirements
| Product Model | Effective Pixels | Sensor Size | Shutter Type | Frame Rate (FPS) | Sensor Type | Data Interface | Color | Actions | 
|---|---|---|---|---|---|---|---|---|
| E3ISPM45000KPA | 45M (8176×5616) | 
                                     
                                                                                    18.93 mm × 13.00 mm
                                                                                                                            1.4"
                                                                             
                                 | 
                                
                                Rolling Shutter | 
                                     
                                                                                    8.1 fps@8176×5616
                                                                                    30.0 fps@4088×2808
                                                                                    8.1 fps@7408×5556
                                                                                    33.0 fps@4088×2808
                                                                                    10.4 fps@8176×4320
                                                                                    34.7 fps@4096×2160
                                                                                    62.5 fps@2048×1080
                                                                                    86.5 fps@1344×720
                                                                             
                                 | 
                                
                                IMX294 (C) | USB3.0 | 
                                                                                                                         | 
                                
                                View Details | 
| E3ISPM45000KPB | 45M (8176×5616) | 
                                     
                                                                                    18.93 mm × 13.00 mm
                                                                                                                            1.4"
                                                                             
                                 | 
                                
                                Rolling Shutter | 
                                     
                                                                                    8.1 fps@8176×5616(C)
                                                                                    30.0 fps@4080×2808(M)
                                                                                    8.1 fps@7408×5556(C)
                                                                                    33.0 fps@3696×2778(M)
                                                                                    10.4 fps@8176×4320(C)
                                                                                    34.7 fps@4096×2160(M)
                                                                                    62.5 fps@2048×1080(M)
                                                                                    86.5 fps@1344×720(M)
                                                                             
                                 | 
                                
                                IMX492 (C,RS) | USB3.0 | 
                                                                                                                         | 
                                
                                View Details | 
| E3ISPM32000KPA | 32M (5600×5600) | 
                                     
                                                                                    12.96 mm × 12.96 mm
                                                                                                                            1.15"
                                                                             
                                 | 
                                
                                Rolling Shutter | 
                                     
                                                                                    8.1 fps@5600×5600
                                                                                    30.0 fps@2800×2800
                                                                                    30.0 fps@1400×1400
                                                                             
                                 | 
                                
                                IMX294 (C) | USB3.0 | 
                                                                                                                         | 
                                
                                View Details | 
| E3ISPM25000KPA | 25M (4928×4928) | 
                                     
                                                                                    5.519 mm × 5.519 mm
                                                                                                                            1/2.3"
                                                                             
                                 | 
                                
                                Rolling Shutter | 
                                     
                                                                                    12 fps@4928×4928
                                                                                    46 fps@2464×2464
                                                                                    100 fps@1648×1648
                                                                             
                                 | 
                                
                                IMX511 (C) | USB3.0 | 
                                                                                                                         | 
                                
                                View Details | 
| E3ISPM21000KPA (Discontinued) | 21M (5280×3954) | 
                                     
                                                                                    17.4 mm × 13.0 mm
                                                                                                                            4/3"
                                                                             
                                 | 
                                
                                Rolling Shutter | 
                                     
                                                                                    17 fps@5280×3954
                                                                                    17 fps@3952×3952
                                                                                    56 fps@2640×1976
                                                                                    67 fps@1760×1316
                                                                                    192 fps@584×438
                                                                             
                                 | 
                                
                                IMX269 (C) | USB3.0 | 
                                                                                                                         | 
                                
                                View Details | 
| E3ISPM20400KPA | 20.4M (4496×4496) | 
                                     
                                                                                    12.32 mm × 12.32 mm
                                                                                                                            1.1"
                                                                             
                                 | 
                                
                                Global Shutter | 
                                     
                                                                                    17.5 fps@4496×4496
                                                                                    64.4 fps@2240×2240
                                                                                    64.4 fps@1120×1120
                                                                             
                                 | 
                                
                                IMX541 (C,GS) | USB3.0 | 
                                                                                                                         | 
                                
                                View Details | 
| E3ISPM20000KPA | 20M (5440×3648) | 
                                     
                                                                                    13.06 mm × 8.76 mm
                                                                                                                            1"
                                                                             
                                 | 
                                
                                Rolling Shutter | 
                                     
                                                                                    15 fps@5440×3648
                                                                                    50 fps@2736×1824
                                                                                    60 fps@1824×1216
                                                                             
                                 | 
                                
                                IMX183 (C,RS) | USB3.0 | 
                                                                                                                         | 
                                
                                View Details | 
| E3ISPM20000KPD | 20M (5440×3648) | 
                                     
                                                                                    13.06 mm × 8.76 mm
                                                                                                                            1"
                                                                             
                                 | 
                                
                                Rolling Shutter | 
                                     
                                                                                    15 fps@5440×3648
                                                                                    50 fps@2736×1824
                                                                                    60 fps@1824×1216
                                                                             
                                 | 
                                
                                IMX283 (C,RS) | USB3.0 | 
                                                                                                                         | 
                                
                                View Details | 
| E3ISPM20000KPC | 20M (5440×3648) | 
                                     
                                                                                    13.06 mm × 8.76 mm
                                                                                                                            1"
                                                                             
                                 | 
                                
                                Rolling Shutter | 
                                     
                                                                                    20 fps@5440×3648
                                                                                    48 fps@2736×1824
                                                                                    58 fps@1824×1216
                                                                             
                                 | 
                                
                                IMX183 (C,RS) | USB3.0 | 
                                                                                                                         | 
                                
                                View Details | 
| E3ISPM18000KPA | 18M (4880×3720) | 
                                     
                                                                                    5.86 mm × 4.46 mm
                                                                                                                            1/2.2"
                                                                             
                                 | 
                                
                                Rolling Shutter | 
                                     
                                                                                    17 fps@4880×3720
                                                                                    40 fps@2448×1836
                                                                                    50 fps@1728×1296
                                                                             
                                 | 
                                
                                SONY Special (C) | USB3.0 | 
                                                                                                                         | 
                                
                                View Details | 
| E3ISPM15600KPA | 15.6M (3952×3952) | 
                                     
                                                                                    13.0 mm × 13.0 mm
                                                                                                                            1.1"
                                                                             
                                 | 
                                
                                Rolling Shutter | 
                                     
                                                                                    17 fps@3952×3952
                                                                                    56 fps@1976×1976
                                                                                    67 fps@1316×1316
                                                                             
                                 | 
                                
                                SONY Special (C) | USB3.0 | 
                                                                                                                         | 
                                
                                View Details | 
| E3ISPM12400KPA | 12.4M (4096×3000) | 
                                     
                                                                                    11.22 mm × 8.22 mm
                                                                                                                            1/1.1"
                                                                             
                                 | 
                                
                                Global Shutter | 
                                     
                                                                                    28.2 fps@4096×3000
                                                                                    100.9 fps@2048×1500
                                                                                    100.9 fps@1024×750
                                                                             
                                 | 
                                
                                IMX545 (C,GS) | USB3.0 | 
                                                                                                                         | 
                                
                                View Details | 
| E3ISPM12300KPA | 12.3M (4096×3000) | 
                                     
                                                                                    14.13 mm × 10.35 mm
                                                                                                                            1.1"
                                                                             
                                 | 
                                
                                Global Shutter | 
                                     
                                                                                    23.4 fps@4096×3000
                                                                                    46.3 fps@2048×1500
                                                                             
                                 | 
                                
                                IMX304 (C,GS) | USB3.0 | 
                                                                                                                         | 
                                
                                View Details | 
| E3ISPM12000KPA | 12M (4000×3000) | 
                                     
                                                                                    7.40 mm × 5.55 mm
                                                                                                                            1/1.7"
                                                                             
                                 | 
                                
                                Rolling Shutter | 
                                     
                                                                                    25 fps@4000×3000
                                                                                    50 fps@2048×1080
                                                                             
                                 | 
                                
                                IMX226 (C) | USB3.0 | 
                                                                                                                         | 
                                
                                View Details | 
| E3ISPM12000KPB | 12M (4056×3040) | 
                                     
                                                                                    6.29 mm × 4.71 mm
                                                                                                                            1/2"
                                                                             
                                 | 
                                
                                Rolling Shutter | 
                                     
                                                                                    30 fps@4056×3040
                                                                                    60 fps@2028×1520
                                                                                    120 fps@1014×760
                                                                             
                                 | 
                                
                                IMX577 (C) | USB3.0 | 
                                                                                                                         | 
                                
                                View Details | 
| E3ISPM12000KPC | 12M (3536×3536) | 
                                     
                                                                                    7.07 mm × 7.07 mm
                                                                                                                            1/1.6"
                                                                             
                                 | 
                                
                                Rolling Shutter | 
                                     
                                                                                    27 fps@3536×3536
                                                                                    60 fps@1768×1768
                                                                             
                                 | 
                                
                                IMX676 (C) | USB3.0 | 
                                                                                                                         | 
                                
                                View Details | 
| E3ISPM09000KPA | 9M (4096×2160) | 
                                     
                                                                                    14.13 mm × 7.45 mm
                                                                                                                            1"
                                                                             
                                 | 
                                
                                Global Shutter | 
                                     
                                                                                    34 fps@4096×2160
                                                                                    60 fps@2048×1080
                                                                             
                                 | 
                                
                                IMX305 (C,GS) | USB3.0 | 
                                                                                                                         | 
                                
                                View Details | 
| E3ISPM09000KPB | 9M (3008×3000) | 
                                     
                                                                                    11.31 mm × 11.28 mm
                                                                                                                            1"
                                                                             
                                 | 
                                
                                Rolling Shutter | 
                                     
                                                                                    40 fps@3008×3000
                                                                                    123 fps@1488×1500
                                                                                    186 fps@992×998
                                                                             
                                 | 
                                
                                IMX533 (C) | USB3.0 | 
                                                                                                                         | 
                                
                                View Details | 
| E3ISPM08300KPA | 8.3M (3840×2160) | 
                                     
                                                                                    6.22 mm × 3.50 mm
                                                                                                                            1/2.5"
                                                                             
                                 | 
                                
                                Rolling Shutter | 
                                     
                                                                                    32 fps@3840×2160
                                                                                    65 fps@1920×1080
                                                                             
                                 | 
                                
                                IMX274 (C) | USB3.0 | 
                                                                                                                         | 
                                
                                View Details | 
| E3ISPM08300KPB | 8.3M (3840×2160) | 
                                     
                                                                                    7.68 mm × 4.32 mm
                                                                                                                            1/1.8"
                                                                             
                                 | 
                                
                                Rolling Shutter | 
                                     
                                                                                    35 fps@3840×2160
                                                                                    60 fps@1920×1080
                                                                             
                                 | 
                                
                                IMX334 (C) | USB3.0 | 
                                                                                                                         | 
                                
                                View Details | 
| E3ISPM08300KPC | 8.3M (3840×2160) | 
                                     
                                                                                    11.14 mm × 6.26 mm
                                                                                                                            1/1.2"
                                                                             
                                 | 
                                
                                Rolling Shutter | 
                                     
                                                                                    45 fps@3840×2160
                                                                                    60 fps@1920×1080
                                                                             
                                 | 
                                
                                IMX485 (C) | USB3.0 | 
                                                                                                                         | 
                                
                                View Details | 
| E3ISPM08300KPD | 8.3M (3840×2160) | 
                                     
                                                                                    11.14 mm × 6.26 mm
                                                                                                                            1/1.2"
                                                                             
                                 | 
                                
                                Rolling Shutter | 
                                     
                                                                                    45 fps@3840×2160
                                                                                    60 fps@1920×1080
                                                                             
                                 | 
                                
                                IMX585 (C) | USB3.0 | 
                                                                                                                         | 
                                
                                View Details | 
| E3ISPM08300KPE | 8.3M (3840×2160) | 
                                     
                                                                                    7.68 mm × 4.32 mm
                                                                                                                            1/1.8"
                                                                             
                                 | 
                                
                                Rolling Shutter | 
                                     
                                                                                    45 fps@3840×2160
                                                                                    60 fps@1920×1080
                                                                             
                                 | 
                                
                                IMX678 (C) | USB3.0 | 
                                                                                                                         | 
                                
                                View Details | 
| E3ISPM08000KPA | 8M (2808×2808) | 
                                     
                                                                                    13.00 mm × 13.00 mm
                                                                                                                            1.15"
                                                                             
                                 | 
                                
                                Rolling Shutter | 
                                     
                                                                                    30 fps@2808×2808(14-bit)
                                                                                    139 fps@1392×1392
                                                                                    139 fps@696×696
                                                                             
                                 | 
                                
                                IMX294 (C) | USB3.0 | 
                                                                                                                         | 
                                
                                View Details | 
| E3ISPM06300KPA | 6.3M (3072×2048) | 
                                     
                                                                                    7.37 mm × 4.92 mm
                                                                                                                            1/1.8"
                                                                             
                                 | 
                                
                                Rolling Shutter | 
                                     
                                                                                    30 fps@3072×2048
                                                                                    38 fps@1536×1024
                                                                             
                                 | 
                                
                                IMX178 (C,RS) | USB3.0 | 
                                                                                                                         | 
                                
                                View Details | 
| E3ISPM06300KPB | 6.3M (3072×2048) | 
                                     
                                                                                    7.37 mm × 4.92 mm
                                                                                                                            1/1.8"
                                                                             
                                 | 
                                
                                Rolling Shutter | 
                                     
                                                                                    59 fps@3072×2048
                                                                                    59 fps@1536×1024
                                                                             
                                 | 
                                
                                IMX178 (C,RS) | USB3.0 | 
                                                                                                                         | 
                                
                                View Details | 
| E3ISPM05100KPA | 5.1M (2448×2048) | 
                                     
                                                                                    6.71 mm × 5.61 mm
                                                                                                                            1/1.8"
                                                                             
                                 | 
                                
                                Global Shutter | 
                                     
                                                                                    63 fps@2448×2048
                                                                                    208.4 fps@1224×1024
                                                                             
                                 | 
                                
                                IMX547 (C,GS) | USB3.0 | 
                                                                                                                         | 
                                
                                View Details | 
| E3ISPM05000KPA | 5M (2448×2048) | 
                                     
                                                                                    8.45 mm × 7.07 mm
                                                                                                                            2/3"
                                                                             
                                 | 
                                
                                Global Shutter | 
                                     
                                                                                    35 fps@2448×2048
                                                                                    50 fps@1224×1024
                                                                             
                                 | 
                                
                                IMX264 (C,GS) | USB3.0 | 
                                                                                                                         | 
                                
                                View Details | 
| E3ISPM03100KPA | 3.1M (2048×1536) | 
                                     
                                                                                    7.07 mm × 5.30 mm
                                                                                                                            1/1.8"
                                                                             
                                 | 
                                
                                Global Shutter | 
                                     
                                                                                    53 fps@2048×1536
                                                                                    85 fps@1024×768
                                                                             
                                 | 
                                
                                IMX265 (C,GS) | USB3.0 | 
                                                                                                                         | 
                                
                                View Details | 
| E3ISPM03100KPB | 3.1M (2048×1536) | 
                                     
                                                                                    5.12 mm × 3.84 mm
                                                                                                                            1/2.8"
                                                                             
                                 | 
                                
                                Rolling Shutter | 
                                     
                                                                                    50 fps@2048×1536
                                                                                    50 fps@1920×1080
                                                                             
                                 | 
                                
                                IMX123 (C) | USB3.0 | 
                                                                                                                         | 
                                
                                View Details | 
| E3ISPM02100KPA | 2.1M (1920×1080) | 
                                     
                                                                                    11.14 mm × 6.26 mm
                                                                                                                            1/1.2"
                                                                             
                                 | 
                                
                                Rolling Shutter | 
                                     
                                                                                    96 fps@1920×1080
                                                                             
                                 | 
                                
                                IMX482 (C) | USB3.0 | 
                                                                                                                         | 
                                
                                View Details | 
| E3ISPM02000KPA | 2M (1920×1080) | 
                                     
                                                                                    7.2 mm × 4.05 mm
                                                                                                                            1/2"
                                                                             
                                 | 
                                
                                Rolling Shutter | 
                                     
                                                                                    125 fps@1920×1080
                                                                             
                                 | 
                                
                                IMX385 (C) | USB3.0 | 
                                                                                                                         | 
                                
                                View Details | 
| E3ISPM01500KPA | 1.5M (1440×1080) | 
                                     
                                                                                    4.968 mm × 3.726 mm
                                                                                                                            1/2.9"
                                                                             
                                 | 
                                
                                Global Shutter | 
                                     
                                                                                    164 fps@1440×1080
                                                                                    320 fps@720×540
                                                                             
                                 | 
                                
                                IMX273 (C,GS) | USB3.0 | 
                                                                                                                         | 
                                
                                View Details | 
Frequently Asked Questions
Learn more about the professional features of E3ISPM series microscopy imaging cameras
- Real-Time Processing: Ultra-Fine™ HISP VP completes demosaicing, auto exposure, white balance, and color correction inside the camera
 - High-Quality Output: Direct output of 8/12-bit high-quality images without post-processing
 - Low CPU Usage: Dramatically reduces computer CPU load, improving overall system efficiency
 - Zero-Latency Imaging: Reduces backend processing delays for true "instant capture"
 
Hardware ISP Integration: Unique in its class for integrating 12-bit ISP within the camera body for more stable performance.
Research-Grade Image Quality: Maintains professional imaging quality while effectively controlling costs, outstanding cost-performance ratio.
Complete Ecosystem: Provides ToupView/ToupLite software and open-source SDK, reducing secondary development costs.
In-Depth Product Introduction
Ultra-Fine™ HISP VP Hardware ISP Engine
Features our proprietary 12-bit hardware image signal processor that performs real-time demosaicing, auto exposure control, auto white balance, and color correction inside the camera. Compared to software ISP, processing speed is improved by more than 10× with latency reduced to microsecond levels, achieving true "what you see is what you get" at the microscope.
Sony Exmor Back-Illuminated CMOS Technology
Features the latest Sony Exmor back-illuminated CMOS sensors with quantum efficiency >70% and dark current <0.1 e⁻/pix/s. The back-illuminated structure significantly improves photoelectric conversion efficiency, particularly suitable for low-light and fluorescence imaging applications, delivering clear images even under extremely low illumination conditions.
USB 3.0 High-Speed Data Transfer
Utilizes USB 3.0 SuperSpeed interface with bandwidth up to 5 Gbps, maintaining real-time preview at over 10 fps even for 45-megapixel models. No additional power supply required, plug-and-play compatibility with various microscope systems.
Flexible Imaging Modes
Supports arbitrary ROI area selection, 2×2/3×3/4×4 pixel binning, and 8-bit/12-bit data depth switching. Exposure time adjustable from 0.1 ms to 15 s, meeting comprehensive requirements from high-speed dynamic observation to long-term accumulative exposure.
Complete Hardware and Software Ecosystem
Provides multi-platform support for Windows/Linux/macOS, bundled with ToupView professional acquisition software and ToupLite lightweight tools. Open SDK interfaces including C/C++, C#/VB.NET, DirectShow, and Twain facilitate system integration and secondary development. All-metal CNC housing design with no fans or mechanical moving parts ensures long-term stable operation.
Key Application Areas
E3ISPM series applications across various microscopy imaging fields
E3ISPM Series Core Advantages
12-Bit Hardware ISP
Ultra-Fine™ HISP VP real-time processing engine
Sony Exmor CMOS
Back-illuminated sensors, quantum efficiency >70%
USB 3.0 High-Speed Transfer
45 MP maintains 10+ fps preview
Flexible Imaging Modes
Arbitrary ROI + multiple pixel binning
Cross-Platform SDK
Windows/Linux/macOS full coverage
Industrial-Grade Design
All-metal CNC housing, fanless silent
Ultra-Low Dark Current
<0.1 e⁻/pix/s, suitable for long exposure
High Cost-Performance
Research-grade image quality, controlled costs